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Universit
Molecules
and
Nano
crystals:
Molecula
r
Recognition
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requirements
r
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y
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o
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Isaac
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aequales
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et
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o
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ys
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and
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ry
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iv
opp
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in
se
partes
every
is
alw
r,
of
the.
.
.
.
and
.
.
.
.
.
.
.
.
.
eezers
y
Mo
.
.
.
.
.
.
.
.
.
Protein
.
.
.
.
Ligands
.
.
.
.
T
.
.
f
.
.
Recognition
.
T
Metho
.
.
The
6
.
2.2.1
.
.
3.2.1
.
.
.
.
vironmen
ramolecula
.
.
.
.
.
2.1.5
2.3.1
SMFS
.
.
.
tro
.
.
.
.
and
.
acto
.
.
Molecular
.
.
.
.
.
Mechanisms
.
Publication
Regulation
.
.
.
PhoB
.
.
.
.
.
and
.
.
.
3.2
.
.
.
.
.
.
olecule
.
.
.
.
.
.
.
.
.
with
.
of
I
.
.
.
.
.
.
.
.
.
2.1
.
.
.
7
.
of
tributions
.
.
DNA
.
Optical
.
.
.
f
.
.
.
.
.
.
SMFS
.
.
.
P
.
.
2.1.6
.
.
duction
for
.
.
.
y
.
.
.
.
.
.
.
.
.
1
.
4
3.1.1
.
T
.
.
.
.
.
3.1.2
2.1.3
F
.
.
.
.
.
.
for
.
.
.
.
F
.
in
.
Theory
.
.
Individual
.
.
IV
.
.
.
.
Single
.
tribution
.
.
.
.
.
.
.
.
.
.
tribution
.
.
Guest-Host
.
.
.
2.1.4
.
.
.
.
.
.
Double-Stranded
.
.
Nativ
(SMFS)
.
Publications
Protein
.
and
.
.
6
.
.
.
AFM
.
.
.
.
.
.
.
.
.
.
3.3.1
o
ds
.
.
.
.
of
.
.
.
Binding
.
2.1.2
Con
Small
.
Systems
.
to
.
with
.
.
.
.
.
.
.
Tw
.
.
.
duction
.
.
.
.
.
.
.
.
.
.
.
.
3
.
Anit
duction
Ranking
.
Native
.
Synthetic
.
oint-Mutated
.
ranscrip-
SMFS
F
.
rs
Simple
3.1
Binding
tro
dels
.
.
.
the
.
.
.
Elasticit
.
.
.
o
.
.
.
DNA
.
.
.
.
.
.
.
.
.
.
.
.
.
General
.
.
.
.
.
2.2
Molecular
.
in
I
ranscription
.
.
.
.
.
.
.
.
in
.
.
The
.
ranscription
.
actor
Immobilization
.
.
.
in
.
.
.
ds
.
.
.
.
.
.
.
SMFS
.
.
.
.
3.1.3
.
orces
.
Kinetics
.
SMFS:
.
Standard
.
.
.
.
.
.
2
.
.
.
.
Publication
.
.
2.1.1
.
.
.
.
.
.
.
.
.
Con
.
.
.
.
.
M
.
.
.
.
.
.
.
DNA-Ligand
.
.
.
.
.
.
.
F
Con
.
.
.
.
.
.
.
.
.
.
Recognition
.
.
.
Sp
.
.
.
r
.
.
.
.
.
.
Molecula
.
.
.
y
3.3
.
Studies
DNA
.
.
e
.
PhoB:
2.3
Role
.
the
I
En
r
.
.
1
Intro
Discrimination
Complexes
.
ectroscop
erstretc
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
Materials
.
Metho
.
.
.
.
.
v
.
Contents
orce
with
the
10
13
14
16
19
21
21
III
28
28
tion
42
42
43
45
48
53
53
the
t.
58
61
63
Sup
The
SMFS
In
of
hing
Ov
In.
.
Exp
.
.
.
.
Switc
Switc
.
.
.
.
.
.
130
.
.
.
.
74
.
.
Quenc
.
.
I
.
.
.
.
.
.
.
.
.
.
.
148
.
149
.
.
.
.
.
.
.
.
.
.
.
.
.
.
SMFS
.
(TIRFM)
.
.
.
.
.
.
Resorc[4]arenes
.
Publication
.
.
.
.
121
.
.
.
.
.
ndix
.
.
.
.
.
.
64
.
.
.
.
.
a
.
.
.
.
97
.
Nano
Metho
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
heo
Molecule
.
.
f
.
Reection
.
106
.
.
.
.
64
.
.
.
.
tribution
.
.
.
.
.
.
.
Publication
.
.
.
.
.
.
68
.
.
.
.
.
.
.
.
.
Con
and
.
wledgements
.
Publications
.
.
.
.
Supramolecular
.
.
.
.
Conferences
.
.
.
.
.
.
Molecular
.
.
.
tro
.
ts
.
.
152
.
.
.
.
.
.
.
.
.
Mec
.
of
Materials
jects
.
.
.
.
.
.
.
Nano
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
77
.
.
.
roved
.
V
.
.
Microscop
.
.
Heterogeneit
.
.
.
.
104
In
tro
Microscop
.
.
.
Publication
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
Calixarenes
.
.
.
.
.
.
.
.
.
.
.
.
.
78
.
.
109
.
I
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
Con
Con
.
.
.
.
.
.
.
.
.
.
.
.
81
.
.
7
.
o
63
135
.
App
.
List
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
Chemistry
tributions
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
Vitae
68
.
Optical
.
SMFS
.
.
.
erimen
.
hes
.
with
.
.
.
Photoswitc
.
.
.
Resorc[4]arene
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
hanical
.
hing
.
Single
.
ob
and
.
.
.
ds
.
.
.
.
.
.
.
.
97
.
Semiconductor
.
crystals
.
.
.
.
.
.
.
.
duction
.
.
.
.
.
.
.
.
.
.
.
.
98
.
Fluorescence
.
hing
.
.
.
.
.
.
.
.
.
.
66
.
5
.
.
.
Imp
.
Publication
.
T
.
.
102
ry
Single
.
Fluorescence
r
y
.
.
Analysis:
.
.
.
.
.
.
.
Chemical
.
.
.
78
.
otal
In
ternal
.
Fluorescence
duction
y
.
.
.
.
.
.
.
VI
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
109
.
Con
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
VI
.
.
VI
.
I
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
tribution
tribution
.
.
.
In
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
121
tribution
Conclusions
.
Outlo
.
k
.
Bibliography
.
Ackno
.
146
.
e
.
148
.
of
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
ten
.
.
.
.
.
.
.
T
.
.
.
to
.
.
.
.
81
.
6
.
Mechanical
.
Emission
.
Control
.
of
.
Individually
.
Addressed
.
Nano
.
crystals
.
97
.
.
.
In
Curriculum
tro
.
duction
.
.
.
.
.
Con
fo
yo
vi
Con
6.3.1
6.3
6.2.1
6.2
6.1.5
6.1.4
6.1.3
6.1.2
6.1.1
6.1
5.2.1
5.2
5.1
Bonds
An
4.3.1
hable
4.3
4.2.1
4.2
4.1.3
and
4.1.2
4.1.1
4.1
tsv
from
atoms,
h
hines
ph
Chemists
The
o
s
from
other
the
blurred.
ened
at
scale
biologists
accompanied
bring
ariet
ical
and
The
b
progress.
on
pre