Cell-Extracellular Matrix Interactions in Cancer

Cell-Extracellular Matrix Interactions in Cancer

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English
314 Pages

Description

Cancer was thought to originate from alterations in intercellular signaling that resulted in the transformation of cells, their uncontrolled proliferation and metastasis. There is now an increasing body of evidence demonstrating that the surrounding matrix and cell-matrix interactions are also major players in this process. Cells adhere and receive signals from various extracellular matrices via transmembrane receptors, the best known of which are the heterodimeric glycoproteins, integrins.

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Published by
Published 23 January 2010
Reads 0
EAN13 9781441908148
Language English

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Cell-Extracellular Matrix Interactions in Cancer