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Endocrine Surgery E-Book


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Endocrine Surgery meets the needs of surgeons in higher training and practising consultants for a contemporary and evidence-based account of this sub-specialty that is relevant to their general surgical practice. It is a practical reference source incorporating the most current information on recent developments, management issues and operative procedures. The text is thoroughly referenced and supported by evidence-based recommendations wherever possible, distinguishing between strong evidence to support a conclusion, and evidence suggesting that a recommendation can be reached on the balance of probabilities.

This is a title in the Companion to Specialist Surgical Practice series whose eight volumes are an established and highly regarded source of information for the specialist general surgeon.

  • The Companion to Specialist Surgical Practice series provides a current and concise summary of the key topics within each major surgical sub-specialty.
  • Each volume highlights evidence-based practice both in the text and within the extensive list of references at the end of every chapter.
  • An expanded authorship team across the series includes additional European and World experts with an increased emphasis on global practice.
  • The contents of the series have been extensively revised in line with recently published evidence.
  • All the chapters reflect the multidisciplinary approach to the subject with up-to-date information on cytopathology, assays of hormones, localisation techniques, anaesthetic requirements, genetic implications and, of course, histopathology and adjuvant treatments.
  • Minimally invasive approaches continue to be promoted and developed throughout the book.
  • The text has a closer emphasis on practical and pragmatic approaches to clinical scenarios.



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Published 21 June 2013
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EAN13 9780702049712
Language English
Document size 11 MB

Legal information: rental price per page 0.0374€. This information is given for information only in accordance with current legislation.

Endocrine Surgery
A Companion to Specialist Surgical Practice
Tom W.J. Lennard, MD LRCP MRCS FRCS(Ed) FRCS [Lond.]
Profe ssor of Surge ry, Ne wcastle Unive rsity, Ne wcast le upon Tyne , UK
Table of Contents
Cover image
Title page
Series Editors' preface
Editor's preface
Evidence-based practice in surgery
Chapter 1: Parathyroid disease
Part 1 Parathyroid disease, syndromes and pathophysiology
Part 2 Operative strategy for the management of parathyroid disease
Chapter 2: The thyroid gland
Surgical pathologies of the thyroid
Surgery of the thyroid
Chapter 3: The adrenal glands
Adrenal incidentaloma
Adrenocortical carcinoma
Phaeochromocytoma and paraganglioma
Cushing's syndrome
Primary hyperaldosteronism
Congenital adrenal hyperplasia
Addison's disease (adrenal insufficiency)
Chapter 4: Familial endocrine disease: genetics, clinical presentation and management
Multiple endocrine neoplasia type 1 (MEN1)
Multiple endocrine neoplasia type 2
Familial hyperparathyroidism (FHP) syndromes
Von Hippel–Lindau disease
Neurofibromatosis type 1 (NF1)
Familial non-medullary thyroid cancer syndromes
Familial adrenocortical disease
Chapter 5: Endocrine tumours of the pancreas
Non-functional pNETs
Other rare endocrine tumours of the pancreas
Malignant pNETs
Chapter 6: Gastrointestinal neuroendocrine tumours
Oesophageal NETs
Gastric NETs
Duodenal NETs
Pancreatic NETs
Jejuno-ileal (small-intestinal) NETs (midgut carcinoids)
Appendiceal NETs
Colon NETs
Rectal NETs
Chapter 7: Clinical governance, ethics and medicolegal aspects of endocrine surgery
Clinical governance
Medicolegal aspects of endocrine surgery
Chapter 8: The salivary glands
Surgical anatomy
Non-neoplastic disease of the salivary glands
Neoplastic disease
Surgical principles
Fifth edition © 2014 Elsevier Limited. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher's permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website:www.elsevier.com/permissions. This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein). First edition 1997 Second edition 2001 Third edition 2005 Fourth edition 2009 Fifth edition 2014 ISBN 978-0-7020-4963-7 e-ISBN 978-0-7020-4971-2
British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library
Library of Congress Cataloging in Publication Data A catalog record for this book is available from the Library of Congress
Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be
mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility.
With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions.
To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.
Printed in China Commissioning Editor:Laurence Hunter Development Editor:Lynn Watt Project Manager:Vinod Kumar Iyyappan Designer/Design Direction:Miles Hitchen Illustration Manager:Jennifer Rose Illustrator:Antbits Ltd
Göran Åkerström, MD, PhD, Professor of Endocrine Surgery, University Hospital, Uppsala University, Uppsala, Sweden
Peter Angelos, MD, PhD, FACS Linda Kohler Anderson Professor of Surgery and Surgical Ethics, The University of Chicago Medicine and Biological Sciences Chief, Endocrine Surgery, Associate Director of the MacLean Center for Clinical Medical Ethics, Chicago, IL, USA
Sebastian Aspinall, MBChB, MD FRCS(Gen Surg) Consultant in General Surgery, Northumbria Healthcare NHS Foundation Trust,North Shields Honorary Consultant Surgeon, General Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
Stephen G. Ball, BSc, MBBS, PhD, FRCP Senior Lecturer, Newcastle University Honorary Consultant, Newcastle Hospitals NHS Trust, Newcastle, UK Richard D. Bliss, MB, FRCS, Consultant Surgeon, Royal Victoria In+rmary, Newcastle upon Tyne, UK
Paula Bradley, BA (Hons), MBBS, MRCS, DOHNS, Otolaryngology, Northern Deanery, Newcastle upon Tyne, UK
Specialty Trainee,
Paul Brennan, FRCPin Clinical Genetics, Institute of Genetic Medicine,, Consultant Newcastle upon Tyne, UK
Robin M. Cisco, MD, Francisco, CA, USA
Fellow, Endocrine Surgery, University of California, San
Justin S. Gundara, MBBS(Hons), Sir Roy McCaughey Surgical Research Fellow (RACS), Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, Australia
Barnard J. Harrison, MBBS, MS, FRCS, Hallamshire Hospital, Sheffield, UK
Consultant Endocrine Surgeon, Royal
Per Hellman, MD, PhDof Surgery, University Hospital, Uppsala University,, Professor Uppsala, Sweden
Ola Hessman, MD, PhD,
Consultant Surgeon and Head of Endocrine Surgery,
University Hospital, Uppsala University, Uppsala, Sweden
William B. Inabnet, III, MD, FACS The Friedman Professor of Surgery Chief, Division of Metabolic, Endocrine and Minimally Invasive Surgery, Mount Sinai Medical Center, New York, NY, USA James A. Lee, MD, Chief, Endocrine/Thyroid Surgery, Columbia University Medical Center, New York, NY, USA
James C. Lee, MBBS, FRACSCandidate, University of Sydney Endocrine, PhD Surgical Unit, Royal North Shore Hospital, Sydney, Australia
Tom W.J. Lennard, MD, LRCP, MRCS, FRCS(Ed), FRCS [Lond.], Surgery, Newcastle University, Newcastle upon Tyne, UK
Professor of
Jeffrey A. Norton, MD, Professor of Surgery, Chief of General Surgery and Surgical Oncology, Stanford University Medical Centre, Stanford, CA, USA
James O'Hara, FRCS (ORL-HNS)Otolaryngologist Head and Neck, Consultant Surgeon, Sunderland Royal Hospital, Sunderland, UK
Barnard J.A. Palmer, MD, MEd, Assistant Professor of Surgery, Division of Metabolic, Endocrine and Minimally Invasive Surgery, Mount Sinai School of Medicine, New York, NY, USA
Stanley B. Sidhu, PhD, FRACSof Surgery, University of Sydney Endocrine, Professor Surgical Unit, Sydney, Australia
Janet Wilson, BSc, MD, FRCSEd, FRCSEng, FRCSLT(Hon) Professor of Otolaryngolgy, Department of Otolaryngology – Head and Neck Surgery, Newcastle University Honorary Consultant Otolaryngologist, The Freeman Hospital, Newcastle upon Tyne, UK
Series Editors' preface
It is now some 17 years since the rst edition of theCompanion to Specialist Surgical Practicewas published. We set ourselves the task of meeting the educational series needs of surgeons in the later years of specialist surgical training, as well as consultant surgeons in independent practice who wished for contemporary, evidence-based information on the subspecialist areas relevant to their general surgical practice. The series was never intended to replace the large reference surgical textbooks which, although valuable in their own way, struggle to keep pace with changing surgical practice. This Fifth Edition has also had to take due account of the increasing specialisation in ‘general’ surgery. The rise of minimal access surgery and therapy, and the desire of some subspecialties such as breast and vascular surgery to separate away from ‘general surgery’, may have proved challenging in some countries, but has also served to emphasise the importance of all surgeons being aware of current developments in their surgical eld. As in previous editions, there has been increasing emphasis on evidence-based practice and contributors have endeavoured to provide key recommendations within each chapter. The eBook versions of the textbook have also allowed the technophile improved access to key data and content within each chapter. We remain indebted to the volume editors and all the contributors of this Fifth Edition. We have endeavoured where possible to bring in new blood to freshen content. We are impressed by the enthusiasm, commitment and hard work that our contributors and editorial team have shown and this has ensured a short turnover between editions while maintaining as accurate and up-to-date content as is possible. We remain grateful for the support and encouragement of Laurence Hunter and Lynn Watt at Elsevier Ltd. We trust that our original vision of delivering an up-to-date a*ordable text has been met and that readers, whether in training or independent practice, will find this Fifth Edition an invaluable resource.
O. James Garden, BSc, MBChB, MD, FRCS(Glas), FRCS(Ed), FRCP(Ed), FRACS(Hon), FRCSC(Hon), FRSE,Regius Professor of Clinical Surgery, Clinical Surgery School of Clinical Sciences, The University of Edinburgh and Honorary Consultant Surgeon, Royal Infirmary of Edinburgh
Simon Paterson-Brown, MBBS, MPhil, MS, FRCS(Ed), FRCS(Engl), FCS(HK),Honorary Senior Lecturer, Clinical Surgery School of Clinical Sciences, The University of Edinburgh and Consultant General and Upper Gastrointestinal Surgeon, Royal Infirmary of Edinburgh