Evidence-Based Nephrology

Evidence-Based Nephrology


864 Pages


This book covers the management of all major renal diseases from an evidence-based and patient-centred approach. With contributions from leading international experts who have a real understanding of evidence-based medicine it provides recommendations on treatment regimens to adopt for individual patients that are most strongly supported by the evidence.

The inclusion of the latest observational and epidemiological data, as well as randomized controlled trial evidence ensures that the book properly reflects the current state of evidence available for nephrological practice. It will be a useful aid to all clinicians, including those caring for transplant and pediatric patients, as it covers the major clinical questions encountered by nephrologists.

This reference is an invaluable source of evidence-based information distilled into guidance for clinical practice which will be welcomed by practitioners, trainees and associated health professionals.



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Published 31 August 2011
Reads 6
EAN13 9781444358230
License: All rights reserved
Language English

Legal information: rental price per page €. This information is given for information only in accordance with current legislation.

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List of contributors, viii
Foreword, xiii
Introduction, xvii
Part 1 Epidemiology of Kidney Disease, 1 1 Epidemiology of Chronic Kidney Disease, 3 William M. McClellan & Friedrich K. Port
2 Chronic Disease Surveillance and Chronic Kidney Disease, 18 Diane L. Frankenfield & Michael V. Rocco
3 Risk Factors for Progression of Chronic Kidney Disease, 29 Eberhard Ritz, Danilo Fliser, & Marcin Adamczak
4 Epidemiology and Screening for Chronic Kidney Disease, 43 Sylvia Paz B. Ramirez
5 Prediction of Risk and Prognosis: Decision Support for Diagnosis and Management of Chronic Kidney Disease, 58 Benedicte Stengel, Marc Froissart, & Jerome Rossert
Part 2 Acute Kidney Injury, 69 6 Definition, Classification, and Epidemiology of Acute Kidney Disease, 71 Eric A. J. Hoste, Ramesh Venkataraman, & John A. Kellum
7 PreRenal Failure and Obstructive Disease, 80 Kevin W. Finkel
8 Hepatorenal Syndrome, 88 Andrés Cárdenas & Pere Ginès
9 Acute Tubular Necrosis, 97 Jay L. Koyner & Patrick T. Murray
10 Radiocontrast Nephropathy, 110 Brendan J. Barrett & Patrick S. Parfrey
11 Miscellaneous Etiologies of Acute Kidney Injury, 122 Kamalanathan K. Sambandam & Anitha Vijayan
12 Renal Replacement Therapy in Acute Kidney Injury, 137 Steven D. Weisbord & Paul M. Palevsky
Part 3 Primary Glomerulonephritis, 147 13 Management of Idiopathic Nephrotic Syndrome in Adults: Minimal Change Disease and Focal Segmental Glomerulosclerosis, 149 Alain Meyrier
14 Membranous Nephropathy, 158 Fernando C. Fervenza & Daniel C. Cattran
15 IgA Nephropathy in Adults and Children, 170 Jonathan Barratt, John Feehally, & Ronald Hogg
16 Membranoproliferative Glomerulonephritis, 183 Richard J. Glassock
Part 4 Secondary Diseases of the Kidney, 197
Hypertensive Renal Disease, 199
17 Hypertension: Classification and Diagnosis, 200 BernardoRodriguezIturbe&Crispı´nMarinVillalobos
18 Management of Essential Hypertension, 207 Eberhard Ritz, Danilo Fliser, & Marcin Adamczak
19 Management of Hypertension in Chronic Kidney Disease, 214 Aimun Ahmed, Fairol H. Ibrahim, & Meguid El Nahas
20 Diagnosis and Management of Renovascular Disease, 223 Jörg Radermacher
21 Diabetes Mellitus, 231 Piero Ruggenenti & Giuseppe Remuzzi
22 Lupus Nephritis, 244 Arrigo Schieppati, Erica Daina, & Giuseppe Remuzzi
23 InfectionRelated Nephropathies, 253 Monique E. Cho & Jeffrey B. Kopp
24 Hepatitis B Virus, 263 M. Aamir Ali, Scott D. Cohen, & Paul L. Kimmel
25 InfectionRelated Nephropathies: Hepatitis C Virus, 272 Dirk R. J. Kuypers
26 PolyomavirusAssociated Nephropathy, 277 Fabrizio Ginevri & Hans H. Hirsch
Toxic Nephropathies, 285
27 Toxic Nephropathies: Nonsteroidal AntiInflammatory Drugs, 286 Wai Y. Tse & Dwomoa Adu
28 Toxic Nephropathies: Environmental Agents and Metals, 294 Richard P. Wedeen
29 The Kidney in Pregnancy, 299 Phyllis August & Tiina Podymow
Part 5 Chronic Kidney Disease, Chronic Renal Failure, 309 30 Progression of Kidney Disease: Diagnosis and Management, 311 Anil K. Agarwal, Nabil Haddad, & Lee A. Hebert
31 Treatment of Anemia in Chronic Kidney Disease, Stages 35, 323 Robert N. Foley
32 Dyslipidemia in Chronic Kidney Disease, 333 Vera Krane & Christoph Wanner
33 Chronic Kidney Disease and Hypertension, 345 Sangeetha Satyan & Rajiv Agarwal
34 Recognition and Management of Mineral and Bone Disorder of Chronic Kidney Disease and EndStage Renal Disease, 353 Donald A. Molony
35 Preparation for Dialysis, 391 Mark G. Parker & Jonathan Himmelfarb
Part 6 Chronic Kidney Disease Stage 5: Hemodialysis, 401 36 When to Start Dialysis and Whether the First Treatment Should Be Extracorporeal Therapy or Peritoneal Dialysis, 403 Raymond T. Krediet
37 Modalities of Extracorporeal Therapy: Hemodialysis, Hemofiltration, and Hemodiafiltration, 410 Kannaiyan S. Rabindranath & Norman Muirhead
38 Dialysis Delivery and Adequacy, 423 Peter Kotanko, Nathan W. Levin, & Frank Gotch
39 General Management of the Hemodialysis Patient, 431 Robert Mactier & David C. Wheeler
40 Infections in Hemodialysis, 441 Behdad Afzali & David J. A. Goldsmith
41 NonAccessRelated Nosocomial Infections in Hemodialysis, 452 Brett W. Stephens & Donald A. Molony
42 Vascular Access for Hemodialysis, 460 Kevan R. Polkinghorne
Part 7 Chronic Kidney Disease Stage 5: Peritoneal Dialysis, 469 43 Selection of Peritoneal Dialysis as Renal Replacement Therapy, 471 Norbert Lameire, Raymond Vanholder, & Wim Van Biesen
44 Small Solute Clearance in Peritoneal Dialysis, 478 Sharon J. Nessim & Joanne M. Bargman
45 Salt and Water Balance in Peritoneal Dialysis, 488 CheukChun Szeto & Philip KamTao Li
46 Impact of Peritoneal Dialysis Solutions on Outcomes, 500 David W. Johnson & John D. Williams
47 Prevention and Treatment of Peritoneal DialysisRelated Infections, 509 Giovanni F. M. Strippoli, Kathryn J. Wiggins, David W. Johnson, Sankar Navaneethan, Giovanni Cancarini, & Jonathan C. Craig
Part 8 Transplantation, 533 48 Evaluation and Selection of the Kidney Transplant Candidate, 535 Bryce Kiberd
49 Evaluation and Selection of the Living Kidney Donor, 545 Connie L. Davis
50 Predictors of Transplant Outcomes, 561 Krista L. Lentine, Robert M. Perkins, & Kevin C. Abbott
51 The Early Course: Induction, Delayed Function, and Rejection, 574 Paul A. Keown
52 Maintenance Immunosuppression, 592 Yves Vanrenterghem
53 Chronic Allograft Nephropathy, 599 Bengt C. Fellström, Alan Jardine, & Hallvard Holdaas
Part 9 Disorders of Electrolytes (Acute and Chronic), 609 54 Overview of Electrolyte and AcidBase Disorders, 611 L. Lee Hamm & Michael Haderlie
55 Hyponatremia, 618 Chukwuma Eze & Eric E. Simon
56 Potassium Disorders, 633 John R. Foringer, Christopher Norris, & Kevin W. Finkel
57 Metabolic Evaluation and Prevention of Renal Stone Disease, 642 David S. Goldfarb
Part 10 Pediatrics, 651
Themes Across Renal Disease and Renal Failure, 653
58 Growth, Nutrition, and Pubertal Development, 654 Lesley Rees
59 Hypertension, Cardiovascular Disease, and Lipid Abnormalities in Children with Chronic Kidney Failure, 669 Elke Wühl & Franz Schaefer
60 Bones Across Kidney Disease and Kidney Failure, 682 Mary B. Leonard
61 Anemia, 693 Susan Furth & Sandra Amaral
Management of Renal Failure/Transplants, 702
62 Renal Transplantation, 703 Pierre Cochat & Justine Bacchetta
63 Peritoneal Dialysis in Children, 723 Jaap W. Groothoff & Maruschka P. Merkus
64 Pediatric Hemodialysis, 738 Stuart L. Goldstein
Specific Pediatric Renal Disease, 745
65 Urinary Tract Infection, Vesicoureteric Reflux, and Urinary Incontinence, 746 Gabrielle Williams, Premala Sureshkumar, Patrina Caldwell, & Jonathan C. Craig
66 Epidemiology and General Management of Childhood Idiopathic Nephrotic Syndrome, 763 Nicholas J. A. Webb
67 Management of SteroidSensitive Nephrotic Syndrome, 774 Elisabeth M. Hodson, Jonathan C. Craig, & Narelle S. Willis
68 SteroidResistant Nephrotic Syndrome, 787 Annabelle Chua & Peter Yorgin
Other Pediatric Renal Diseases, 806
69 HenochSchonlein Nephritis and Membranoprolifertive Glomerulonephritis, 807 Sharon Phillips Andreoli
70 Cystinosis, 818 William G. vant Hoff
Index, 823
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