157 Pages

ABCA1 expression and function under physiological and pathological conditions [Elektronische Ressource] : novel links between apoptosis, atherosclerosis and haemostasis / Christiane Albrecht

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ABCA1 EXPRESSION AND FUNCTION UNDER PHYSIOLOGICAL AND PATHOLOGICAL CONDITIONS - NOVEL LINKS BETWEEN APOPTOSIS, ATHEROSCLEROSIS AND HAEMOSTASISChristiane AlbrechtChair of Physiology, Center of Life and Food Sciences Weihenstephan, Technische Universität MünchenSynopsis of own scientific work for the acquisition of the degree “Habilitation” according §9 Habilitationsordnung presented by the Technische Universität München, December 9, 2003October 2005Submitted to Center of Life and Food Sciences Weihenstephan – Technische Universität MünchenTABLE OF CONTENTSTABLE OF CONTENTSPreface III1 Introduction 42 Own research projects 92.1 ABCA1 and cholesterol homeostasis/HDL deficiency 92.2 ABCA1 and phosphatidylserine translocation/Scott syndrome 112.3 ABCA1 and diseases of immune hyperactivity 152.4 ABCA1 and vascular diseases/atherosclerosis 182.5 ABCA1 and glucose levels 262.6 ABCA1 and disorders in pregnancy 283 Conclusions 344 Perspectives 365 Bibliography 366 Summary 50Acknowledgements 50Appendix1 Relevant publications2 Other publications in the context of ABC transporter proteins3 Other publications (diverse)4 AbbreviationsIIPREFACEPREFACEThis work reviews own research activities attempting to unravel physiological transport mechanisms within or out of cells which are based on the ATP-binding cassette transporter A1 (ABCA1).



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Published 01 January 2005
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Language English
Document size 32 MB