Characterisation of oskar 3'UTR RNA domains involved in early RNA localisation and translational repression [Elektronische Ressource] / presented by Helena Jambor

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Dissertation submitted to the Combined faculties of Natural Sciences and Mathematics of the Rupertus-Carolus-University Heidelberg for the degree of Doctor in Natural Sciences Presented by Helena Jambor (Diplom-Biologin) Born in Uelzen/Germany Oral examination: 18th of November 2008 Examiners: Prof. Dr. Matthias Hentze und Prof. Dr. Eduard Hurt Characterisation of oskar 3’UTR RNA domains involved in early RNA localisation and translational repression. Examiners: Prof. Dr. Matthias Hentze und Prof. Dr. Eduard Hurt Contents Abstract 1Zusammenfassung 2 1. Introduction………………………………………………………………………………………..3 1.1. D.melanogaster as a model organism 3 1.1.1. Historical perspective 3 1.1.2. D.melanogaster life style: live fast, die young 3 1.1.3. Fast embryogenesis accelerates development 4 1.1.4. D.melanogaster oogenesis 4 1.2. Local protein activity 6 1.2.1. The functions and mechanisms of local protein activities 6 1.2.2. Localised mRNAs in D.melanogaster oogenesis 7 1.3. oskar mRNA regulation in the early development of D.melanogaster 10 1.3.1. Biological function of Oskar 10 1.3.2. oskar mRNA localisation 12 1.3.3.

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Published 01 January 2009
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Language English
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