Hypoxic regulation of glyceraldehyde-3-phosphate dehydrogenase in HPV-positive non-tumorigenic and tumorigenic cells [Elektronische Ressource] / presented by Anna Hitschler

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Dissertationsubmitted to theCombined Faculties for the Natural Sciences and for Mathematicsof the Ruperto-Carola University of Heidelberg, Germanyfor the degree ofDoctor of Natural SciencesPresented byDipl.-Biotech. Anna Hitschlerborn in Heidelberg Oral examination: October 2010Hypoxic regulation of glyceraldehyde-3-phosphate dehydrogenase in HPV-positive non-tumorigenic and tumorigenic cellsReferees: Prof. Dr. Rainer ZawatzkyProf. Dr. Frank RöslFür meine ElternIn Gedenken an meinen Großvater Franz BallikIndexAbstract ....................................................................4......................................................Zusammenfassung ..........................................................5..............................................1. Introductio.n. ............................................................7.................................................1.1 Human papillomaviruses and cervical cancer ..............................7......................1.1.1 HPV genome organization and viral life cycle ..........................8...................1.1.2 Transcriptional regulation of the early HPV genes .....................1.0..............1.1.3 The central role of AP-1 ............................................11.................................1.1.4 The Ets transcription factor family ...................................1.3.........................1.1.5 Physiological role of Net and the impact on tumorigenesis....

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Published 01 January 2010
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Language English
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