Investigation of the catalytic mechanism of RNase P [Elektronische Ressource] : the role of divalent metal ions and functional groups important for catalysis / vorgelegt von Simona Cuzic-Feltens

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Investigation of the catalytic mechanism of RNase P: the role of divalent metal ions and functional groups important for catalysis Dissertation zur Erlangung des Doktorgrades der Naturwissenschaften (Dr. rer. nat.) dem Fachbereich Pharmazeutische Chemie der Philipps-Universität Marburg vorgelegt von Simona Cuzic - Feltens aus Corlateni-Botosani/Rumänien Marburg/Lahn 2006 Vom Fachbereich Pharmazeutische Chemie der Philipps-Universität Marburg als Dissertation am:.............................angenommen Erstgutachter: Prof. Dr. rer. nat. Roland K. Hartmann Zweitgutachter: Prof. Dr. rer. nat. Albrecht Bindereif Tag der mündlichen Prüfung am: 15.02.2006 Content 1 INTRODUCTION.............................................................................................................................. 1 1.1 RIBOZYME................................................................................................................................................ 1 1.2 RNASE P .................................................................................................................................................. 2 1.2.1 The RNA subunit of RNase P (P RNA) ............................................................................. 2 1.2.2 The active center of RNase P............................................................................................

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Published 01 January 2006
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