Structural mechanism of the recovery-stroke in myosin II molecular motor at atomic detail [Elektronische Ressource] / presented by Sampath Kumar Koppole

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D I S S E R T A T I O NSubmitted to theCombined Faculties for Natural Sciences and Mathematicsof the Ruprecht-Karls-University of Heidelberg, Germanyfor the degree ofDoctor of Natural SciencesPresented by:Dipl.-Chem. Sampath Kumar KoppoleBorn in Nidamanuru, IndiathOral Examination: 12 January 2007Structural mechanism of therecovery-stroke in Myosin II molecularmotor at atomic detail.Referees:Prof. Dr. Joachim P. SpatzProf. Dr. Jeremy C. SmithStructural mechanism of therecovery-stroke in Myosin II molecular motorat atomic detail.Sampath Kumar KoppoleDedicated to my Family ......Asatho Maa Sad Gamaya;Thamaso Maa JyothirMrithyor Maa Amritham Gamaya. Atharvana VedaLead me from untruth to truth;Lead me from darkness to light;Lead me from death to immortality. Atharvana VedaThe work in this thesis was performed under the guidance ofDr. Stefan Fischer, Head of the Computational Biochemistry group atIWR (Interdisziplinares¤ Zentrum fur¤ Wissenschaftliches Rechnen),University of Heidelberg, Germany.CONTENTSList of Figures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . viiiList of Tables . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ixSummary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xiZusammenfassung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xiiiAcknowledgements . . . . . . . . . . . . . . . . . . . . . . .

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Published 01 January 2007
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D I S S E R T A T I O N
Submitted to the
Combined Faculties for Natural Sciences and Mathematics
of the Ruprecht-Karls-University of Heidelberg, Germany
for the degree of
Doctor of Natural Sciences
Presented by:
Dipl.-Chem. Sampath Kumar Koppole
Born in Nidamanuru, India
thOral Examination: 12 January 2007Structural mechanism of the
recovery-stroke in Myosin II molecular
motor at atomic detail.
Referees:
Prof. Dr. Joachim P. Spatz
Prof. Dr. Jeremy C. SmithStructural mechanism of the
recovery-stroke in Myosin II molecular motor
at atomic detail.
Sampath Kumar KoppoleDedicated to my Family ......Asatho Maa Sad Gamaya;
Thamaso Maa Jyothir
Mrithyor Maa Amritham Gamaya.
Atharvana Veda
Lead me from untruth to truth;
Lead me from darkness to light;
Lead me from death to immortality.
Atharvana Veda