How long does prilocaine last? - AASraw(prilocaine powder supplier)
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How long does prilocaine last? - AASraw(prilocaine powder supplier)

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5 Pages
English

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http://www.aasraw.com/products/prilocaine/ - Prilocaine is a local anesthetic(prilocaine local anesthetia)of the amino amide type,In its injectable form , it is often used in dentistry.

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Published 03 March 2018
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How long does prilocaine last?-AASraw(prilocaine powder supplier)
www.aasraw.comaas15@aasraw.com
1. What is prilocaine?
Prilocaine is a local anesthetic(prilocaine local anesthetia)of the amino amide type first prepared by Claes Tegner and Nils Löfgren. In its injectable form , it is often used in dentistry. It is also often combined with lidocaine as a topical preparation for dermal anesthesia , for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).
2. Raw material of prilocaine
Raw material of prilocaine is the main ingredient for making prilocaine injectable form or prilocaine cream form.Prilocaine powderis white crystalline powder, Prilocaine powder/prilocaine local anethetia is chemically designated as propanamide, N-(2-methylphenyl)-2-(propylamino), has an octanol: water partition ratio of 25 at pH 7.4, and has the following characteristic:
prilocaine local anesthetic description Name prilocaine CASNo.721-50-6Purity 99% Apperance white crystalline powder MolecularFormulaC13H20N2OMolecular Weight 220.31 Melt Point 37-38Storage Temp RT Manufacturermow.wwsraa.caw Package Foil bag Payment method WesternUnion, MoneyGram, Bitcoin, Bank wire Delivery within 12hours after payment
How long does prilocaine last?-AASraw(prilocaine powder supplier)
www.aasraw.comaas15@aasraw.com
3. Prilocaine injection form and Prilocaine cream form?
Prilocaine injection form
Prilocaine Injection form,is a sterile, non pyrogenic isotonic solution that contains a local anesthetic agent and is administered parenterally by injection. Prilocaine Injection, contains prilocaine raw powder, which is chemically designated as propanamide, N-(2-methyl-phenyl) -2- (propylamino)-, monohydrochloride.
Prilocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action.
prilocaine dosage:
How long does prilocaine last?-AASraw(prilocaine powder supplier)
www.aasraw.comaas15@aasraw.comAdult: Maxillary infiltration: initially 1–2mL; max recommended dose within a 2-hour period: <70kg: 8mg/kg; ≥70kg: 600mg. Elderly, debilitated, acutely ill: reduce dose.
Children: <10yrs: use Clarks rule to calculate dose.
Contraindications: Congenital or idiopathic methemoglobinemia.
Interactions: Risk of methemoglobinemia with sulfonamides, acetaminophen, acetanilid, aniline dyes, benzocaine, chloroquine, dapsone, naphthalene, nitrates and nitrites, nitrofurantoin, nitroglycerin, nitroprusside, pamaquine, para-aminosalicylic acid, phenacetin, phenobarbital, phenytoin, primaquine, quinine.
Prilocaine cream form
Prilocaine cream form is an emulsion in which the oil phase is a eutectic mixture of lidocaine powder and prilocaine powder in a ratio of 1:1 by weight. This eutectic mixture has a melting point below room temperature and therefore both local anesthetics exist as a liquid oil rather than as crystals. It is packaged in 5 gram and 30 gram tubes. Lidocaine-Prilocaine cream contains lidocaine powder 25 mg, prilocaine raw powder 25 mg, polyoxyethylene fatty acid esters (as emulsifiers), carboxypolymethylene (as a thickening agent), sodium hydroxide to adjust to a pH approximating 9, and purified water to 1 gram. Llidocaine-prilocaine Cream contains no preservative, however it passes the USP antimicrobial effectiveness test due to the pH. The specific gravity of EMLA (lidocaine and prilocaine) Cream is 1.00.
4. How long does prilocaine last?
Excellent skin numbing results are obtained 30 minutes to 1 hour post application.
Don't be impatient: give the product time to work! That way, you obtain the most benefit out of it.
Please don't fall for other products that promise "instant numbing". Unless the skin is broken, is not going to happen.
That said, some areas of the body numb faster than others. For example, if you put some of the gel on your lips (the red part), you will feel numb - really numb - in less
How long does prilocaine last?-AASraw(prilocaine powder supplier)
www.aasraw.comaas15@aasraw.comthan ten minutes. That is because the skin there is very permeable. Try it yourself, once you get the product, and you will believe it!
However, most other areas of the body take more time, because the skin elsewhere is thicker, with many keratinized layers that act as a barrier.
TOPICAINE® is formulated to overcome this barrier, because it contains skin permeation enhancers. These are substances that temporarily and reversibly increase the permeability of the stratum corneum - the skin barrier.
In addition, the product needs some time to penetrate to where the pain receptors are located, deep into the dermis. In some areas, like the lips, the numbing action can be felt much faster because the nerve receptors are located very superficially. Most other locations of the body the receptors are located deeper, and it takes longer to reach them.
If the application time is 30 minutes, the skin numbing effect will last approximately 1 hour. If you apply the product for 1 hour, your skin will remain numb for about 2 hours, even after you remove it!
As a rule of thumb, remember this:
the duration of the numbing is about twice as long as the application time, and the longer the application time, the longer and deeper the numbing effect
5. Prilocaine brand name
Prilocaine injection form: Citanest
Prilocaine cream form: Emla
6. Prilocaine side effects
The serious prilocaine side effects may include:
severe burning, stinging, or sensitivity where the medicine is applied; swelling or redness; sudden dizziness or sleepiness after medicine is applied; bruising or purple appearance of the skin; or unusual sensations of...
How long does prilocaine last?-AASraw(prilocaine powder supplier)
www.aasraw.comaas15@aasraw.com7. Buy prilocaine powder online from prilocaine powder supplier-AASraw
AASraw is a professional manufacturer that provide high quality steroids raw material, sex hormone, fat loss hormone, local anesthetic. Asprilocaine powder supplier, AASraw guarantee all the powder purity no less than 98%, with competitive price and safely delivery.